This formulation combines vitamins B2 (riboflavin), B6 (pyridoxal 5’-phosphate), B12 (as methylcobalamin) and folate as L-5-methyltetrahydrofolate (L-5-MTHF). Together, the B vitamins help maintain homocysteine levels within the normal range. This promotes cardiovascular health as well as brain and cognitive health.^2-4

Folate (L-5-MTHF)

But not everyone’s body can utilize traditional folic acid supplements efficiently; many people cannot effectively convert folate to its bioactive 5-MTHF form (L-5-methyltetrahydrofolate), leaving them vulnerable to low blood folate levels (and higher-than-desired homocysteine).⁵ So Homocysteine Resist delivers 5000 mcg of 5-MTHF in each capsule.

Vitamin B6 (pyridoxal 5'-phosphate)

Vitamin B6 is used in the body for many functions, including helping to metabolize proteins, fats, and carbohydrates. Traditional forms of B6 must be converted to pyridoxal 5'-phosphate before your body can use it, but Homocysteine Resist contains 100 mg of pyridoxal 5'-phosphate that’s ready to work right from the start.⁶

Vitamin B2 (riboflavin) and Vitamin B12 (methylcobalamin)

The body naturally converts vitamin B2 (riboflavin) to its riboflavin-5'-phosphate form, which it then uses for energy production (among other functions).⁷ Vitamin B12 supports brain and heart health by helping to maintain healthy homocysteine levels already within normal range. And methylcobalamin is one of the active forms of B12 utilized in metabolic reactions.^8,9