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Trial Finds Heart Attack Patients Who Took CoQ10 Recovered Faster
People who take coenzyme Q10 (CoQ10) after a heart attack may recover faster than those who do not, according to the analysis of an ongoing clinical trial of 120 patients who received stents, antiplatelets and statin drugs after their cardiac events. The findings were reported January 28, 2024, in BMC Cardiovascular Disorders.1
About half of the participants received 30 milligrams of CoQ10 per day. At one- and three-month follow-up examinations, these participants experienced greater increases in ejection fraction (which is reduced in heart failure) than the group not receiving CoQ10. At three months, B-type natriuretic peptide (which, when elevated, can indicate heart failure) had declined to a greater extent among those who received CoQ10.
These improvements suggest that CoQ10 supported early heart function recovery. Why might that be? Investigation of CoQ10’s mechanisms of action in a concurrent mouse study suggested that the answer may lie in the inflammatory response: there was less inflammation in the hearts of mice receiving CoQ10 than those who did not take it.
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Apply What You’ve Learned: Heart Failure
- Heart failure occurs when the heart fails to pump adequate blood to support healthy circulation. It is often caused by other conditions, including coronary heart disease, high blood pressure, heart inflammation, cardiomyopathy or arrhythmia.2
- Lifestyle practices that include a healthy diet are recommended for heart failure patients. Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diets, which provide a high amount of plant foods, micronutrients, antioxidants and fiber, have been suggested.3 Physician-approved exercise is also beneficial.4
- Clinical studies have shown benefits for the herb hawthorn in patients with mild chronic heart failure.5 A meta-analysis of clinical trials found improvement in breathing, fatigue and more in chronic heart failure patients who received hawthorn extract.6
- Among other nutrients, omega-3 fatty acids may also be helpful for people with heart failure.7,8 Heart failure patients are advised to discuss the use of additional nutrients with their healthcare providers.
References
- Pan W et al. BMC Cardiovasc Disord. 2024 Jan 28;24(1):76.
- National Heart, Lung, and Blood Institute. What is Heart Failure? Updated 2022 Mar 24. https://www.nhlbi.nih.gov/health/heart-failure
- Kerley CP. Nutr Res Rev. 2019 Jun;32(1):1-27.
- Downing J et al. J Am Coll Cardiol. 2011 Aug 2;58(6):561-9.
- Koch E et al. 5. Planta Med. 2011 Jul;77(11):1123-8.
- Pittler MH et al. Am J Med. 2003 Jun 1;114(8):665-74.
- Oikonomou E et al. Clin Nutr. 2019 Jun;38(3):1188-1197.
- Tavazzi L et al. Lancet. 2008 Oct 4;372(9645):1223-30.
Featured Life Extension Magazine® Article
Superfood: Coriander
By Holli Ryan, RD, LD/N
Coriander, which also goes by the name cilantro, has been used for thousands of years, specifically for gastrointestinal disorders. Recent research adds evidence to coriander’s gastrointestinal benefits and has revealed beneficial effects for the heart, including support of healthy lipid levels, blood pressure and more.
A clinical trial found that coriander seed powder given to diabetics was associated with a decrease in blood glucose and cholesterol in comparison with a placebo when given for six weeks.
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Overview Affirms CoQ10 Association with Reduced Heart Failure Mortality
An overview of systematic reviews and meta-analyses of clinical trials published June 23, 2023, in Food & Function concluded a possible beneficial effect for CoQ10 on cardiac function, which was associated with fewer hospitalizations and decreased mortality from heart failure.
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Review the risk factors and causes of heart failure, along with current standards of care and a number of emerging treatment strategies.
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